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Biological engineering

Five professors from MIT tackle Major Cancer Challenges

Five MIT researchers—Michael Birnbaum, Regina Barzilay, Brandon DeKosky, Seychelle Vos, and Ömer Yilmaz—are part of winning teams for Cancer Grand Challenges 2024. Each team, made up of international, interdisciplinary cancer researchers, will receive $25 million over five years. Associate Professor of Biological Engineering Michael Birnbaum is heading Team MATCHMAKERS, comprised of co-investigators Regina Barzilay (Engineering Distinguished…

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The search algorithm uncovers almost 200 novel types of CRISPR systems.

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The search algorithm has uncovered almost 200 new types of CRISPR systems.

Scientists from the McGovern Institute for Brain Research at MIT, the Broad Institute of MIT and Harvard, and the National Center for Biotechnology Information at the National Institutes of Health, have developed a new search algorithm to find enzymes of interest in vast microbial sequence databases. This algorithm, called Fast Locality-Sensitive Hashing-based clustering (FLSHclust), discovered…

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Nearly 200 new types of CRISPR systems have been identified via a search algorithm.

Researchers at MIT, Harvard, and the National Institutes of Health have utilized a new search algorithm to identify 188 different types of rare CRISPR systems in bacterial genomes. This data holds potential to advance genome-editing technology, enabling more precise treatments and diagnostics. The algorithm, developed in the lab of prominent CRISPR researcher, Professor Feng Zhang uses…

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The search algorithm uncovers almost 200 novel types of CRISPR systems.

Scientists from the McGovern Institute for Brain Research at MIT, the Broad Institute of MIT and Harvard, and the National Center for Biotechnology Information at the National Institutes of Health have developed a new algorithm that can sift through massive amounts of genomic data to identify unique CRISPR systems. Known as Fast Locality-Sensitive Hashing-based clustering…

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The search algorithm has unveiled close to 200 new variants of CRISPR systems.

Microbial sequence databases hold a vast array of information about enzymes and other molecules that could be utilized in biotechnology applications. However, the sheer size of these databases has made it challenging to efficiently search for specific enzymes of interest. Researchers from the McGovern Institute for Brain Research at MIT, the Broad Institute of MIT and…

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Bridging the gap between design and production of optical gadgets.

Researchers from MIT and the Chinese University of Hong Kong have developed a digital simulator that seeks to improve photolithography's precision, often used in computer chips and optical devices manufacture. The process uses light to etch intricate designs onto surfaces, but minor discrepancies often cause devices' final performance to deviate from designers' initial intentions. The…

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MIT researchers harness artificial intelligence to discover potential new antibiotic classes.

Using deep learning, a form of artificial intelligence, researchers at MIT have discovered a group of compounds that can eliminate methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant bacterium that causes over 10,000 deaths in the US annually. The compounds, which display low toxicity against human cells, are considered good potential drug candidates. In a paper published in…

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