National Institutes of Health (NIH)

Researchers from the Massachusetts Institute of Technology (MIT), Brigham and Women’s Hospital, and Duke University have used tissue models and machine-learning algorithms to identify how specific drugs pass through the digestive tract. The knowledge can help improve patient treatments, as certain drugs could interfere with each other if they depend on the same protein transporters.…

Researchers from the Massachusetts Institute of Technology (MIT), Brigham and Women’s Hospital, and Duke University have developed an innovative strategy to identify the transporter proteins used by different drugs in the body’s gastrointestinal (GI) tract. The method, which employs tissue models and machine-learning algorithms, aims to improve drug administration by enabling predictions of drug interactions…

A multi-institutional team of researchers from MIT, Brigham and Women’s Hospital, and Duke University have developed a strategy that uses machine learning and tissue models to identify transport proteins that different drugs interact with in the gastrointestinal (GI) tract. When a drug is taken orally, it must pass through the lining of the digestive tract.…

Researchers from MIT, Brigham and Women’s Hospital and Duke University have developed a multipronged strategy to identify which transporter proteins drugs use to pass through the GI tract. This could not only improve patient treatment by revealing which drugs might interact unfavorably with each other, but also enhance the development of new drugs by informing…

Researchers from MIT, Brigham and Women’s Hospital, and Duke University have developed a strategy to identify the transporter proteins used by different drugs to exit the digestive tract. This knowledge could improve patient treatment, as drugs relying on the same transporter can interfere with each other and should not be prescribed together. The researchers adapted…

A team of researchers from MIT, Brigham and Women’s Hospital, and Duke University have worked together to develop a method for identifying how different drugs exit the digestive system. This is a key question in pharmacology, as it is often associated with drug interactions and efficacy. In this study, the researchers utilized a combination of…

Scientists from MIT, Brigham and Women’s Hospital, and Duke University have developed a method to track how oral drugs pass through the human digestive tract. This research is considered key as it can help predict potential drug interactions which improve patient treatment. The research used a combination of tissue models and machine learning algorithms. Oral…

Researchers from MIT, Brigham and Women’s Hospital, and Duke University have developed a research approach to identify how different drugs exit the digestive tract. The method uses tissue models and machine-learning algorithms to understand which transporters are used by drugs, revealing how a commonly prescribed antibiotic and blood thinners can interfere with each other. Transporter…

Researchers from MIT, Brigham and Women’s Hospital, and Duke University have developed a novel approach combining machine-learning algorithms and tissue models to identify the specific transporters used by drugs in the gastrointestinal tract. This breakthrough could lead to improvements in patient treatment and drug development. Transporter proteins within the gastrointestinal system enable drug absorption. These proteins…

Researchers from MIT, Brigham and Women’s Hospital, and Duke University have developed a strategy to identify how different drugs are transported through the digestive tract. This new multipronged strategy combines the use of tissue models and machine learning algorithms to comprehend which transporters help various drugs to pass through the digestive tract. This is an important…

Researchers from MIT, Duke University, and Brigham and Women’s Hospital have designed an innovative strategy to identify the specific transporters that different drugs utilize. The study could potentially improve patient treatment as it uncovered that certain common drugs can interfere with each other if they rely on the same transporter. The process is based upon…

Oral drugs must pass through the lining of the digestive tract to be absorbed into the bloodstream and take effect. Certain proteins present in the cells lining the digestive tract, known as transporters, aid this process, but for many drugs, the specific transporters they utilize are unknown. This knowledge could enhance patient treatment regimens as…